Alli slimming pills have become the subject of controversy again as a new study suggests they could cause organ failure.
The American research says that Alli, which claims to stop your body absorbing fat, attacks a key enzyme that could lead to liver and kidney damage.
It has also been claimed that taking it could stop anti-cancer drugs from being effective.
Professor Bingfang Yan from the Rhode Island University lead the study, stating that there has been a, 'drastic increase in toxicity' among people using the slimming pills.
According to the Daily Express, the professor claims that the use of Orlistat in Alli inhibits carboxylesterase-2, an enzyme which detoxifies the liver, kidney and digestive tract.
The Professor explained that, 'When the activity of this enzyme drops in those organs, toxicity increases or the efficacy of some drugs is altered.'
He added that the increase in toxicity, 'has been linked to severe liver failure, acute pancreatic failure and acute renal (kidney) failure.'
GlaxoSmithKline who produce the pills refute the allegations, saying that the European regulator reaffirmed the safety of Orlistat earlier in the year.
A spokesperson from the drugs company said, 'The results of this study [by Prof Yan] in particular are based on laboratory methods in the lab, not in humans or animals, and they aren't consistent with the wealth of data from patients who have been treated with orlistat.'
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